Characteristic | Description |
---|---|
Active Ingredient | Tadalafil 20mg |
Form | Soft Gel Capsule |
Onset of Action | 15-30 Minutes |
Duration | Up to 36 Hours |
Visit Cialis Super Active Site |
Pharmacokinetics
The pharmacokinetics of Cialis Super Active, containing Tadalafil 20mg, is characterized by rapid absorption and prolonged efficacy. Tadalafil is metabolized predominantly in the liver, specifically by the cytochrome P450 3A4 (CYP3A4) enzyme. The medication exhibits a high oral bioavailability and reaches peak plasma concentrations within two hours post-administration. Unlike some erectile dysfunction medications, Cialis Super Active maintains effectiveness for up to 36 hours, which offers an extended therapeutic window.
Elimination is primarily through the fecal route (approximately 61%), with the remainder excreted in urine. The half-life of Tadalafil in the body is approximately 17.5 hours, which supports its prolonged duration of action. Pharmacokinetic properties remain consistent across different populations, but patients with hepatic or renal impairments may experience altered elimination rates, necessitating dose adjustments.
Mechanism of Action
Cialis Super Active works by enhancing blood flow to the penile tissue, facilitating erection during sexual arousal. Tadalafil 20mg inhibits phosphodiesterase type 5 (PDE5), an enzyme responsible for the degradation of cyclic guanosine monophosphate (cGMP). By blocking PDE5, Tadalafil increases levels of cGMP, leading to smooth muscle relaxation and vasodilation in the corpus cavernosum. The resultant blood influx engorges the penile tissue, producing a firm erection suitable for sexual intercourse.
Distinct from other PDE5 inhibitors, Tadalafil’s extended duration is attributed to its slower dissociation from the PDE5 enzyme. This allows Cialis Super Active to offer a flexible window for spontaneous sexual activity without the necessity for precise timing relative to dosage.
Warnings & Precautions
Before taking Cialis Super Active, patients must consider certain precautions. Tadalafil 20mg is contraindicated in individuals with known hypersensitivity to any component. Caution is advised for patients with cardiovascular conditions such as heart failure, arrhythmias, or recent myocardial infarction. It is imperative to avoid concurrent use with nitrate medications due to the risk of severe hypotension.
Patients should disclose their complete medical history to healthcare providers, including liver or kidney disease and retinitis pigmentosa. A thorough assessment of potential drug interactions is essential, particularly with antihypertensives, alpha-blockers, and potent CYP3A4 inhibitors.
Cialis Super Active Storage
Proper storage of Cialis Super Active ensures its effectiveness. Keep the medication in its original packaging to protect from moisture. Store it at room temperature, away from excessive heat and light. Maintain a storage environment below 30°C (86°F). Do not store in bathrooms, as humidity may compromise the integrity of the capsules.
Ensure that Cialis Super Active is out of reach of children and pets. Dispose of any expired or unused medication responsibly, adhering to local regulations regarding pharmaceutical waste.
Cialis Super Active Side Effects
Cialis Super Active may produce side effects, though they are generally mild. Common adverse reactions include headache, indigestion, back pain, and muscle aches. These effects usually resolve within 48 hours. In rare cases, more severe reactions such as sudden vision loss, priapism, or hearing impairment may occur, necessitating immediate medical attention.
Patients should monitor for any unexpected changes in their health status. It is crucial to report persistent or bothersome side effects to a healthcare professional for assessment and guidance.
Purchasing Cialis Super Active Without a Prescription
Purchasing Cialis Super Active without a prescription raises significant safety concerns. Tadalafil 20mg is a prescription medication, and unsupervised use may lead to adverse outcomes. A healthcare provider should evaluate individual suitability and determine the appropriate dosage.
Online pharmacies may offer Cialis Super Active without a prescription. However, patients should exercise caution as these sources might supply counterfeit or unsafe products. Verification of the pharmacy’s credentials and seeking recommendations from reputable healthcare professionals can help mitigate risks.
Guideline | Recommendation |
---|---|
Dosage Adjustment | Consult with healthcare provider |
Storage Conditions | Keep at room temperature |
- Consider potential interactions
- Avoid mixing with nitrates
- Ensure proper storage
Responsible usage and adherence to prescribed guidelines maximize the benefits of Cialis Super Active, ensuring safe and effective treatment.
Data origin:
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